DUBLIN--(BUSINESS WIRE)--The 'Live Cell Imaging Market by Product (Instruments, Consumables, Software, Services), Application (Cell Biology, Drug Discovery), Technology (Time-lapse Microscopy, FRET), End User (Contract Research Organization, Research Institutes) - Global Forecast to 2025' report has been added to ResearchAndMarkets.com's offering.
The Global Live Cell Imaging Market Size is Projected to Reach USD 2.8 Billion by 2025 from USD 1.8 Billion in 2020, at a CAGR of 8.8% during the Forecast Period.
Article Title: Human cytomegalovirus long noncoding RNA4.9 regulates viral DNA replication. Article Snippet:.Imaging was performed on a Zeiss Axio Observer Z1 widefield microscope equipped with an X63 oil-immersion objective and an Axiocam 506 mono camera using ZEN imaging software (Zeiss). The live cell imaging market consists of several major players, including Becton, Dickinson and Company, Carl Zeiss, and Leica Microsystems, among many others. The companies are implementing certain strategic initiatives, such as mergers, new product launches, acquisitions, and partnerships that help them in strengthening their market positions.
The market for live cell imaging is driven primarily by the factors such as the growing adoption of high-content screening techniques in drug discovery, rising incidence of cancer, growth in research funding, and rising government funding in regenerative medicine research. However, high cost of high-content screening systems will hinder the overall adoption of live cell imaging systems and thereby restrain market growth in the coming years.
By instrument type, the microscopes segment holds the largest market share during the forecast period.
Based on type, the live cell imaging instruments market is segmented into microscopes, standalone systems, cell analyzers, and accessories. The microscopes segment accounted for the largest share of the live cell imaging market in 2019. The large share of this segment can be attributed to the increasing studies into cell behavior and the need to correlate multiple events and markers with cell morphology, favorable funding scenario for R&D in microscopy, rising focus on regenerative medicine, technological advancements in microscopes, and favorable regulatory procedures to launch new instruments in the market.
By application, the stem cells segment is expected to register the highest CAGR during the forecast period.
Based on application, the live cell imaging market is segmented into cell biology, stem cells, developmental biology, and drug discovery. The stem cells segment is projected to register the highest CAGR during the forecast period. Factors such as increasing stem cell research activities and investments.
Asia Pacific (APAC) is projected to witness the highest growth during the forecast period.
The APAC market is estimated to register the highest CAGR during the forecast period. The growth in this market can be attributed to the government initiatives for research on stem cell therapy, increasing aging population, the rising prominence of regenerative medicine research, increasing number of researchers in Japan, growth of preclinical/clinical research in China, favorable changes in foreign direct investment (FDI) regulations in the pharmaceutical industry in India, and growth of the pharmaceutical and biopharmaceutical sectors in South Korea.
Market Dynamics
Drivers
- Growing Adoption of High-Content Screening Techniques in Drug Discovery
- Rising Incidence of Cancer
- Growing Availability of Research Funds
- Rising Government Funding in Regenerative Medicine Research
Restraints
- High Cost of High-Content Screening Systems
Opportunities
- Emerging Markets
- Applications of Hcs in Personalized Medicine
Challenges
- Maintaining Cell Viability and the Cellular Environment in Cell Cultures
- Dearth of Skilled Professionals
COVID-19 Impact on the Live Cell Imaging Market
Companies Mentioned
- Becton, Dickinson and Company
- Biotek Instruments, Inc.
- Bruker Corporation
- Carl Zeiss Ag
- Cytosmart Technologies
- Danaher Corporation
- Etaluma, Inc.
- GE Healthcare
- Keyence Corporation
- Logos Biosystems (Aligned Genetics Inc.)
- Merck KGaA
- Nanoentek Inc.
- Nanolive Sa
- Nikon Corporation
- Olympus Corporation
- Perkinelmer Inc.
- Phase Focus Ltd.
- Sartorius Ag
- Sony Biotechnology Inc.
- Thermo Fisher Scientific
For more information about this report visit https://www.researchandmarkets.com/r/yfv9ui
Zeiss AxioCam MR/HR Adapter
| Summary: | Interfaces Zeiss AxioCam medium resolution and high resolution color and monochrome cameras |
| Author: | Henry Pinkard |
| License: | Source code cannot be made available |
| Platforms: | Windows |
| Devices: | AxioCam MRm/MRc/HRm/HRc, MRm/MRc/HRm/HRc Rev. 2, and MRm/MRc/HRm/HRc Rev. 3 (tested with MRm Rev. 2, MRm Rev. 3, MRc Rev. 3, HRm Rev. 2, HRm Rev. 3); MRc5 |
Because of built in delays in the AxioCam's image acquisition, there is a delay of approximately 200ms between when Micro-Manager sends the command to open the shutter and when the AxioCam's exposure begins. If over exposure of the sample is a concern, it is highly recommended that hardware triggering is used with these cameras. Refer to the below descriptions of hardware triggering to do so (All images and text below ©2010 Carl Zeiss MicroImaging GmbH. All rights reserved.).
Trigger-Out
Via a supplementary cable the AxioCam has the capability of sending out aTTL trigger pulse to an external device, for example a mechanical shutter. Thistrigger pulse can be used to synchronizethe exposure of the camera and the task of the external device, as you canspecify the delay between sending outthe trigger signal and actually starting the acquisition.
To meet the requirements of the device you are using, you caninvert the polarity that you want thesignal to have.
Trigger-In
The exact time of exposure can be triggered from outside the camera. When the trigger-in is enabled and an acquisition function is called, the camera will delay the acquisition and wait for a trigger-in signal to be sent from an external device until it invokes the exposure.The following graphic demonstrates the two camera models' reaction to the trigger signal when performing a triggered acquisition. An acquisition request is sent out at each T, the acquisition takes place at an A:
NOTE: The trigger OUT of the AxioCam HR / MR expects a TTL signal.
Trigger Timing
Due to different hardware and trigger mechanisms, the precise calculation ofthe camera's timing when involvong the trigger IN / OUT is a bit difficult anddepends on the camera model's internal design.
The following charts demonstrate, how an example acquisition using bothtrigger IN and trigger OUT could look like and explain how to preciselycalculate the timing.
| AxioCam HR / MR |
| The AxioCam HR / MR accepts only positive values for the trigger OUT delay, ranging from 0 to 255 row cyles, Filestream driver download for windows 10. where 1 cycle lasts 154 µs (AxioCam HR) respectively 99 µs (AxioCam MR).
|
| AxioCam MRc5 / MR Rev.3 / HS |
| The AxioCam MRc5 / MR Rev.3 / HS allows both positive and negative values for the trigger OUT delay, ranging from +4095 row cycles to -4095 row cyles, where 1 cycle lasts 244 µs. |
| - negative delay |
| If the specified trigger OUT delay is longer than the interval for the fixed idle rows and clearing the sensor, the trigger OUT is sent directly after the initialization has been completed. The camera performs the cleanoutand then waits an appropriate amount of time until the exposition is invoked.
|
Carl Zeiss Vision
| If the specified trigger OUT delay is shorter than the interval for the fixed idle rows and clearing the sensor, the camera starts the sensor cleanout right after the initialization was finished and delays sending the triggerOUT signal to achieve the desired trigger OUT delay.
|
| - positive delay |
|
--Henry Pinkard 10:58, 2nd January 2013 (PDT)
IEEE 1394 driver on Windows 7
Windows 7 comes with two versions of the IEEE 1394 bus driver (default and 'legacy'). I had trouble getting an AxioCam MRc5 recognized with the default one. This might be dependent on the motherboard and IEEE 1394 adapter. To switch between the default and 'legacy' drivers, follow the instructions mentioned here: http://social.technet.microsoft.com/Forums/en-US/itprovistahardware/thread/c2e39b2c-0558-43cb-865e-9f9db3e4f5ed/
Carl Zeiss Lens
Using the Legacy driver may also help with cases where the message '(0)McamAcquisition error 22' pops up and Micro-Manager becomes unresponsive.
--Mark Tsuchida
Drivers Carl Zeiss Imaging 1394 Digital Camera
Carl Zeiss Company